Effectiveness of COVID-19 Vaccine Three Doses in Mortality Reduction among COVID-19 Infected Elderly in Samut Prakan Province

Authors

  • Rungsan Wongboonnak Samut Prakan Provincial Public Health Office

Keywords:

COVID-19 vaccine effectiveness, elderly, COVID-19 infection, COVID-19 related mortality, 3-dose vaccine

Abstract

This study retrospectively investigated the effectiveness of the vaccine in real-life situations. The objective focused on the reduction in deaths of elderly people infected with COVID-19 who received the complete 3-dose COVID-19 vaccine compared to those who did not. Data were collected from the electronic database of the Samut Prakan Provincial Health Office, linked to the Ministry of Public Health’s database on vaccination. Data were collected retrospectively from January 1, 2022 to March 31, 2022. Result: The study found that there were 5,891 COVID-19 elderly individuals resulting in 56 deaths. Of those 2,236 patients who received the complete 3-dose vaccine faced 5 deaths, while 3,655 who did not face 51 deaths; odds ratio of 0.16 (95% CI = 0.06-0.40) or an 84% reduction in mortality (p < 0.001). Conclusion: Elderly individuals who received the complete 3-dose vaccine had a reduced risk of mortality if contracted COVID-19 in real-life situations. Therefore, the results should be disseminated to encourage complete 3-dose COVID-19 vaccine in elderly individuals.

References

COVID-19 Situation Administration Center. Coronavirus disease 2019 situation [Internet]. 2021 Dec 31 [cited 2022 Apr 12]. Available from: https://media.thaigov.go.th/uploads/public_img/source/311264.pdf. (in Thai)

World Health Organization. Regulation and prequalification [Internet]. [cited 2022 Apr 12]. Available from: https://www.who.int/teams/regulation-prequalification/eul/covid-19.

Urairerkkul C. Measuring the effectiveness of the vaccine against COVID-19 [Internet]. 2021 Jul 30 [cited 2022 Apr 12]. Available from: http://doh.hpc.go.th/bs/indexDisplay.php?id=595. (in Thai)

Emergency Operations Center, Department of Disease Control. Report on the situation of corona virus infection 2019 [Internet]. 2022 Jan 7 [cited 2022 Apr 12]. Available from: https://ddc.moph.go.th/viralpneumonia/file/situation/situation-no731-070165.pdf. (in Thai)

Hfocus. Open elderly information: if infected with COVID-19, high risk of death! [Internet]. 2022 Mar 4 [cited 2022 Apr 12]. Available from: https://www.hfocus.org/content/2022/03/24644. (in Thai)

Dadras O, SeyedAlinaghi S, Karimi A, Shamsabadi A, Qaderi K, Ramezani M, et al. COVID-19 mortality and its predictors in the elderly: a systematic review. Health Science Reports 2022;5(3):e657. doi: 10.1002/hsr2.657.

Sritipsukho P, Siribumrungwong B, Tantiyavarong P, Satdhabudha A, Damronglerd P, Jaru-ampornpan P. Effectiveness of the COVID-19 vaccine in Thailand: studies in real situations [Internet]. 1st year report. 2022 Mar [cited 2022 May 12]. Available from: https://kb.hsri.or.th/dspace/handle/11228/5535?locale-attribute=th. (in Thai)

Ranzani OT, Hitchings MDT, Dorion M, Lang D’Agostini T, Cardoso de Paula R, Ferreira Pereira de Paula O, et al. Effectiveness of the CoronaVac vaccine in older adults during a gamma variant associated epidemic of covid-19 in Brazil: test negative case-control study. BMJ 2021;374:n2015. doi: 10.1136/bmj.n2015.

Arregocés-Castillo L, Fernández-Niño J, Rojas-Botero M, Palacios-Clavijo A, Galvis-Pedraza M, Rincón-Medrano L, et al. Effectiveness of COVID-19 vaccines in older adults in Colombia: a retrospective, population-based study of the ESPERANZA cohort. The Lancet, Healthy Longevity 2022;3(4):e242-e252. doi: 10.1016/S2666-7568(22)00035-6.

Downloads

Published

29-06-2023

How to Cite

1.
Wongboonnak R. Effectiveness of COVID-19 Vaccine Three Doses in Mortality Reduction among COVID-19 Infected Elderly in Samut Prakan Province. J Health Syst Res [internet]. 2023 Jun. 29 [cited 2025 Jun. 21];17(2):364-71. available from: https://he04.tci-thaijo.org/index.php/j_hsr/article/view/3180

Issue

Section

original article