Journal of the Office of DPC 12 Songkhla

An evaluation of disease prevention and control and health hazards missions after the transfer of the Sub-district Health Promotion Hospitals to Provincial Administrative Organization In Regional Health 12

Dararat Sompaosong — 2025-02-18

The evaluation research based on the CIPP Model, with the objective of assessing the performance of disease prevention and control missions, health hazard, of the Sub-district Health Promotion Hospitals (SHPHs) following their transfer to the Provincial Administrative Organizations (PAO) in Health Region 12. This includes 28 SHPHs in Phatthalung, Pattani, Songkhla, and Satun provinces. Selected purposively of 69 individuals from the PAO and a accidental sampling of 403 citizens from the transferred SHPH areas were selected. Data was collected through interviews, satisfaction surveys, and productivity assessments reviewed by experts (0.9). Qualitative data were analyzed through content analysis and triangulation, while quantitative data were analyzed using descriptive statistics. The study results are as follows: 1. Context: Policies, work systems, and communication were clear, though management practices differed based on the size of the SHPHs and their relationships with networks. 2.Inputs: Leadership was found to be flexible according to the context. There was an increase in personnel (before median 6 (3,18); after median 9 (6,29)) and budget from subsidies. Access to medications/supplies and services from CUP and PAO only had access to HDC. 3. Process: Disease prevention, detection, control, and emergency response were carried out according to standard guidelines. 4.Product:In the 28 SHPHs: 1) Disease Prevention: Vaccine coverage for DTP3 (target ≥90) and MMR2 (target ≥95) did not meet the criteria (50%, 54%) and showed a decrease in performance (50%, 54%). 2) Disease detection: Screening
and monitoring of diabetes and hypertension did not meet the criteria (32%, 50%) and showed a decrease in performance (64%, 71%). 3) Disease Control/Emergency Response: Successfully controlled the second generation of dengue fever outbreaks at 50%. Satisfaction levels showed that the general public had a highest level of satisfaction ( 4.75±0.71) while stakeholders had a hight level of satisfaction ( 3.85 ± 0.71). Recommendations: There should be a focus on developing the potential of PAO personnel in data access and increasing the recording of disease prevention and control and health hazard according to epidemiological principles to enhance disease surveillance and control efforts.

The Effectiveness of public health services provided by the Sub-district Health Promoting Hospital before and after transfer to Nakhon Si Thammarat Provincial Administrative Organization

Manu Taluengpet — 2025-02-18

This research was a descriptive retrospective study. This study aimed to investigate the effectiveness of
the providing public health services of the Sub-district Health Promoting Hospital By averaging the percentage
of work covering 7 missions, consisting of: 1. Maternal and child health work 2. Immunization work 3.Screening
4. Surveillance 5. Nutrition work 6. Surveillance of health promotion and environmental health and
7. Promotional work and Prevent mental health problems, including 81 activities devolution to Nakhon
Si Thammarat Provincial Administrative Organization let's compare. Using statistics to analyze differences.
The study population was a Sub-district health promoting Hospitals devolution to the Nakhon Si Thammarat
Provincial Administrative Organization, fiscal year 2023, totaling 36 places. The data collection tool was a form of
recording data on public health operations of Sub-district Health Promoting Hospitals devolution to the Nakhon
Si Thammarat Provincial Administrative Organization from reports in Health Data Center system for 2022 and
2023 of the Information and Communication Technology Center, Office of the Permanent Secretary, Ministry of
Public Health. Data was analyzed using descriptive statistics, including means and percentages, and inferential
statistics, specifically the paired t-test. The finding showed that when testing the difference in mean coverage
of the work of the Sub-district health Promoting Hospital. between before and after devolution to the Nakhon
Si Thammarat Provincial Administrative Organization by setting the significance value at 0.05. It was found that
before the devolution the average percentage of work was higher than after devolution with statistical significance
of 19 activities, after had a statistically significant higher percentage of work than before devolution
amounting to 18 activities. The mean percentage of work before and after devolution was not significantly
different, amounting to 44 activities. Will be more visible results of the providing public health services of
the Sub-district Health Promoting Hospital After devolution to the Nakhon Si Thammarat Provincial Administrative
Organization the performance was as good as before the devolution. Even though some activities would be
less productive. There should be a monitoring team. Continuously supervise the work of devolution personnel.
To provide additional knowledge, acknowledge problems, obstacles and find solutions together.

Diagnostic Performance of SARS-CoV-2 Rapid Antigen Test in Relation to Realtime - PCR Ct (Cycle threshold) Value

Panuttha Chaimuti — 2025-02-18

The outbreak of SARS-Cov-2 is more widespread very fast around the world. SARS-Cov-2 infection can be diagnosed with a simple, rapid and accurate test method. To evaluate the performance of the SARS-CoV-2 Rapid test kit, It is important to compare it to the Real-time RT-PCR method, which is the standard method for diagnosing COVID-19. The VTRUST Antigen test kit was utilized in this study to analyze Nasopharyngeal swab samples from 368 patients suspected of being infected when they visited Hat Yai Hospital.There were 163 positive results and 205 negative results. The results of the SARS-CoV-2 antigen diagnostic performance test with the relationship between Ct values by RT-PCR method. We found that Positive results by SARS-CoV-2 antigen method when confirmed by Real-time RT-PCR method found the target gene ORF1ab with an average cycle threshold (Ct) value of 18.6 ± 3.8, the N gene with an average cycle threshold (Ct) value of 17.6 ± 3.87 and the E gene with an average cycle threshold (Ct) value of 18.03 ± 3.81. There were 12 reported negative results but confirmed as positive byReal-time RT-PCR method with the target gene ORF1ab with an average cycle threshold (Ct) value of 33.05 ± 3.86 (min 23.28, max 37.47) the N gene with an average cycle threshold (Ct) value of 31.99 ± 3.31 (min
23, max 35.12) and the E gene with an average cycle threshold (Ct) value of 32.36 ± 3.88 (min 22.97, max 37.42)
has a sensitivity and specificity of 93.10%, 99.48% respectively. The efficiency of the SARS-CoV-2 Rapid test kit
with a sensitivity and specificity can be used to screen infected people well, helping to control the spread of
the covid-19 virus.

Evaluation of Influenza surveillance system of Koh Lanta Hospital, Koh Lanta District, Krabi Province, 2022

Wirayut Sontimuang — 2025-02-18

In 2022, Koh Lanta District experienced an increase in influenza cases. The coverage of Influenza
reported cases based on the epidemiological surveillance report (Report 506) in Koh Lanta Hospital was 42.6%.
Additionally, the transfer of responsibilities from the sub-district health promoting hospitals in the area to
the Provincial Administrative Organization may impact the influenza surveillance and control system. This study
aims to examine the disease reporting process, analyze the quantitative and qualitative aspects of the influenza
surveillance system, and provide guidelines for improving and developing an effective disease control system in
the area following the transfer of responsibilities to the Provincial Administrative Organization. A cross-sectional
study employs both quantitative and qualitative methods. It involves a review of patient information reported
in the 506 reporting system related to influenza. The study examines inpatient data from medical records of
patients treated at Koh Lanta Hospital in 2022, focusing on cases coded under ICD-10: J09-J11. A total of 237
cases were identified, along with 348 patients presenting with diseases that have similar symptoms, as defined by
the Epidemiology Division. Additionally, interviews were conducted with individuals involved in the surveillance
system at all levels. The results of the study found that Among total of 585 medical records were evaluated
according to disease definitions and reporting guidelines. Of these, 286 cases generated 101 reports, showing
a low sensitivity of 10.50 percent. Only 74 cases met the criteria for disease surveillance, with a high positive
predictive value of 73.27 percent. All 74 reports were complete, with gender and diagnosis date accuracy at
100 percent, age accuracy at 94.06 percent, and timeliness also at 100 percent. While stakeholders recognized
the importance of disease reporting, continuity in reporting was affected by transfers from the Subdistrict Health
Promoting Hospital to the Provincial Administrative Organization, resulting in low data utilization at the latter level.
Overall, the influenza surveillance system at Koh Lanta Hospital is moderately effective, but improvements in
data sensitivity are needed. Therefore, emphasis should be placed on effectively communicating the guidelines
for implementing reporting definitions related to the disease surveillance system to all relevant personnel.
It is crucial to optimize the use of the surveillance system, which includes developing a disease reporting
framework to facilitate collaboration between public health agencies and provincial administrative organizations.
This approach will enable stakeholders to leverage information effectively in designing disease prevention and
control measures that are tailored to the specific needs of the area.

Systematic review: the relationship of immune family gene in Anopheles mosquito (Diptera: Culicidae) on Plasmodium infection

Kerati Kittiwattanawong — 2025-02-18

The study of genes in the immune system of Anopheles mosquitoes, specifically the JAK-STAT pathway, in relation to their response mechanisms to malaria infection, in conjunction with the genes NOS, TEP1, SOCS, and HPX15, collaborate within the JAK-STAT pathway to mount immune responses against malaria infection. This study employs a systematic literature review approach with a research guideline that suggests if Anopheles mosquitoes possess suspect genes that increase their vector potential for malaria transmission, these mosquitoes are more likely to serve as primary vectors. Conversely, if fewer suspect genes are present, the potential for malaria transmission decreases. Inhibiting the expression of genes, particularly those that enhance the vector potential of Anopheles mosquitoes, is a strategy to reduce their competency to transmit malaria. The systematic review results related to confirmed suspect genes associated with malaria transmission indicate that inhibiting the expression of these genes can reduce the development of malaria parasites. For example, inhibiting the HPX15
gene significantly reduces the number of ookinetes forming in the midgut of Anopheles mosquitoes. Additionally, the SOCS and PIAS genes act as negative feedback mechanisms for JAK-STAT to stop the activation of the NOS gene, which prevents hyper-immunity. However, within 24 hours post-infection, ookinetes fully mature and are ready for implantation. This systematic review provides an understanding of the immune systems of different
Anopheles mosquito species, including the roles and functions of individual genes. The knowledge gained can be
utilized to develop strategies to inhibit the expression of genes that enhance the vector potential of Anopheles
mosquitoes for malaria transmission. This represents a novel approach to preventing and controlling malaria
outbreaks.