The link between psoriatic arthritis comorbidity index and clinical characteristics in patients with psoriatic arthritis (Eng)
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Abstract
Objectives: Psoriatic arthritis comorbidity index (PsACI) was developed specifically to assess comorbidity in psoriatic arthritis (PsA) patients. This study aimed to investigate the association between PsaCI and clinical characteristics in patients with PsA
Methods: This is a cross sectional study including PsA patients who visited the Rheumatology Clinic at Hospital Raja Permaisuri Bainun. Their clinical characteristics and comorbidities were recorded.
Results: This study population consisted of 172 patients with PsA. There were 77 males (44.8%) and 95 females (55.2%). Hypertension (59.9%) was the most common comorbidity, followed by dyslipidemia (46.5%) and diabetes mellitus (36.1%). The PsACI score was significantly associated with age and obesity (p<0.001). Further analysis revealed that both the age of onset for psoriasis and the age of onset for PsA exceeding 45 years were positively correlated with higher PsACI scores. PsACI did not correlate with the multiple domains of PsA, the site of psoriasis or treatment regimen given.
Conclusions: The findings underscore the critical importance of managing comorbid conditions in PsA patients, especially among those with an earlier age of psoriasis onset, older patients with PsA, and those with obesity. The results showed the overall comorbidity burden may be influenced more by patient-specific factors rather than disease-specific factors. Further research is needed to better understand the interplay between comorbidities and PsA.
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