The risk factors associated with the mortality of pediatric septic shock in Surin Hospital
Keywords:
Risk factors, Septic shock, Pediatric, mortality predictorAbstract
Background: Septic shock is the most critical condition that has high mortality rate within 24-72 hours after diagnosis. Appropriate management in this condition may be used. However, in developing countries have inadequate resources, leading to inadequate management and increasing the rate of mortality.
Objective: To analyze mortality risk factors in pediatric septic shock.
Method: A retrospective chart review was conducted on patients treated in the pediatric intensive care unit (PICU) of Surin hospital from 2020 to 2024. Clinical characteristic, laboratory parameters, and treatment profiles were collected. Logistic regression analysis was employed to identify risk factors associated with 28-day mortality.
Results: A total of 120 subjects were included in this study and 28-day mortality rate was 39.2%. On the multivariate analysis, the risk factors significantly associated with the mortality were the failure to administer antibiotics within the 60-minute period after diagnosed (OR 6.4, 95%CI 1.7-24.8, p value 0.007), received the corticosteroid (OR 3.9, 95%CI 1.0-14.3, p value 0.044), and multiple organ dysfunction syndrome (MODS) (OR 14.7, 95%CI 3.6-60.7, p value < 0.001).
Conclusion: The failure to administer antibiotics within the first 60-minute, received the corticosteroid and multiple organ dysfunction syndrome (MODS) were significant variable risk factors associated with 28-day mortality in pediatric septic shock.
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