Respiratory manifestation of hospitalized pediatric COVID-19 At Maharat Nakhon Ratchasima Hospital
Keywords:
COVID-2019, SARS-CoV-2, children, respiratory manifestationAbstract
Background: The coronavirus disease 2019 (COVID-19) has been found to present a wide range of symptoms and severity in pediatric patients.
Objective: To study the respiratory symptoms in pediatric patients diagnosed with coronavirus disease 2019 (COVID-19) at Maharaj Nakhon Ratchasima Hospital.
Methods: A retrospective descriptive study, was conducted using the medical records of children aged from 29 days to 15 years who were diagnosed with COVID-19 and were admitted to the pediatric ward at Maharaj Nakhon Ratchasima Hospital, from January 1 2022, to June 30, 2022 (6 months).
Results: There were 174 participants enrolled, mostly under 5 years old with median age of 3 years and 50.6% were females. Preexisting comorbidities were found in 26.4% including obesity 10.3% and immunocompromised/cancer 5.7%. The most common initial diagnosis was common cold (57.5%) followed by pharyngitis (13.8%) and pneumonia (11.5%). Higher rates of pneumonia were found in patients with comorbidities. Most (94.8%) were admitted to the cohort ward. The median length of stay was 4 days. Most patients (89.1%) did not require oxygen supplementation. Respiratory supports were required for 19 patients (10.9%) including mechanical ventilation 8 patients (4.6%), high-flow nasal canula 5 patients (5.2%), and nasal canula 2 patients (1.1%). The most common complication was acute respiratory failure (4.6%). There was no deaths in this study.
Conclusion: Most hospitalized patients with COVID-19 were symptomatic, The most common respiratory diagnosis was upper respiratory tract infection. Pneumonia was more frequently observed in patients with comorbidity.
Downloads
References
World Health Organization, Coronavirus disease (COVID-19), Weekly Epidemiological Update.2020 [Cited January 2020].
Case SM, Son MB. COVID-19 in pediatrics. Rheum Dis Clin North Am. 2021;47:797-811.
กรมควบคุมโรค กระทรวงสาธารณสุข. สถานการณ์ผู้ติดเชื้อ COVID-19 ภายในประเทศ. [อินเตอร์เน็ต]. 2022 [Cited 1 ตุลาคม 2565]. Available from:https://ddc.moph.go.th/covid19-daily-dashboard.
Huang R, Zhu L, Xue L, Liu L, Yan X, Wang J, et al. Clinical findings of patients with Coronavirus disease 2019 in Jiangsu province, China: A retrospective, multi-center study. PLoS Negl Trop Dis. 2020 May;14:e0008280.
Xu L, Mao Y, Chen G. Risk factors for 2019 novel Coronavirus disease (COVID-19) patients progressing to critical illness: A systematic review and meta-analysis. Aging (Albany NY). 2020;12:12410-21.
Cen Y, Chen X, Shen Y, Zhang XH, Lei Y, Xu C, et al. Risk factors for disease progression in patients with mild to moderate Coronavirus disease 2019-a multi-centre observational study. Clin Microbiol Infect. 2020;26:1242-7.
Wu Z, McGoogan JM. Characteristics of and important lessons from the Coronavirus Disease 2019 (COVID-19) outbreak in China: summary of a report of 72,314 cases from the Chinese Center for Disease Control and Prevention. JAMA. 2020;323:1239–42.
Dong Y, Mo X, Hu Y, Qi X, Jiang F, Jiang Z, et al. Epidemiology of COVID-19 among children in China. Pediatrics. 2020;145:1-10.
กรมการแพทย์ กระทรวงสาธารณสุข. แนวทางเวชปฏิบัติ การวินิจฉัย ดูแลรักษา และป้องกันการติดเชื้อในโรงพยาบาล กรณีโรคติดเชื้อไวรัสโคโรนา 2019 (COVID-19) สำหรับแพทย์และบุคลากรสาธารณสุข. ฉบับปรับปรุง 22 มีนาคม 2565. นนทบุรี: กรมการแพทย์; 2565.
Posfay-Barbe KM, Wagner N, Gauthey M, Moussaoui D, Loevy N, Diana A, et al. COVID-19 in children and the dynamics of infection in families. Pediatrics. 2020;146:e20201576.
Choi YY, Kim YS, Lee SY, Sim J, Choe YJ, Han MS. Croup as a manifestation of SARS-CoV-2 Omicron variant infection in young children. J Korean Med Sci. 2022;37:e140.
Cozzi G, Sovtic A, Garelli D, Krivec U, Silvagni D, Corsini I, et al. SARS-CoV-2-related bronchiolitis: A multicenter international study. Arch Dis Child. 2023;108:e15.
Lee EP, Mu CT, Yen CW, Hsia SH, Lin JJ, Chan OW, et al. Predictors of disease severity and outcomes in pediatric patients with croup and COVID-19 in the pediatric emergency department. Am J Emerg Med. 2023;72:20-6.
Oualha M, Bendavid M, Berteloot L, Corsia A, Lesage F, Vedrenne M, et al. Severe and fatal forms of COVID-19 in children. Arch Pediatr. 2020;27:235–8.
Shekerdemian LS, Mahmood NR, Wolfe KK, Riggs BJ, Ross CE, McKiernan CA, et al. International COVID-19 PICU Collaborative. Characteristics and outcomes of children with Coronavirus Disease 2019 (COVID-19) infection admitted to US and Canadian Pediatric Intensive Care Units. JAMA Pediatr. 2020;174:868-73.
Derespina KR, Kaushik S, Plichta A, Conway EE Jr, Bercow A, Choi J, et al. Clinical manifestations and outcomes of critically ill children and adolescents with Coronavirus Disease 2019 in New York City. J Pediatr. 2020;226:55-63.
Woodruff RC, Campbell AP, Taylor CA, Chai SJ, Kawasaki B, Meek J, et al. Risk factors for severe COVID-19 in children. Pediatrics. 2022;149:e2021053418.
Opasatian R, Ungchusak P. Demographic data and risk factors for pneumonia in children with
COVID-19: Thai J Pediatr. 2022;61:93-102.
Zachariah P, Johnson CL, Halabi KC, Ahn D, Sen AI, Fischer A, et al. Epidemiology, clinical features, and disease severity in patients with Coronavirus disease 2019 (COVID-19) in a children’s hospital in New York city, New York. JAMA Pediatr. 2020;174:e202430.
Arentz M, Yim E, Klaff L, Lokhandwala S, Riedo FX, Chong M, et al. Characteristics and outcomes of 21 critically ill patients with COVID 19 in Washington State. JAMA. 2020;323:1612-4.
Lighter J, Phillips M, Hochman S, Sterling S, Johnson D, Francois F, et al. Obesity in patients younger than 60 years is a risk factor for Covid-19 hospital admission. Clin Infect Dis. 2020 Jul 28;71:896.
Peacock TP, Brown JC, Zhou J, Thakur N, Newman J, Kugathasan R, et al. The SARS-CoV-2 variant, Omicron, shows rapid replication in human primary nasal epithelial cultures and efficiently uses the endosomal route of entry. bioRxiv. 2021.12.31.474653.
Shi T, Pan J, Moore E, Katikireddi SV, Docherty AB, Fenton L, et al. Risk of COVID-19 hospitalizations among school-aged children in Scotland: A national incident cohort study. J Glob Health. 2022;12:05044.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2026 The Royal College of Pediatricians Of Thailand

This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.