Prevalence of Abnormal Pap Smear in Maharat Nakhon Ratchasima Hospital

Abstract

Introduction: Cervical cancer is the 2^nd most moss malignancy after breast cancer among Thai women. The International Agency for Research on Cancer (IARC) of World Health Organization (WHO) reported that the incidence of new cases of cervical cancer in 2010 was 530,000 cases/year. In the case of cervical cancer in Thai women, the age-standardized incidence rate was 24.5 cases/100,000 women. A Pap smear can detect abnormalities before they turn into cancer. Objective: To study the prevalence of abnormal Pap smear in Maharat Nakhon Ratchasima Hospital. Patients & Methods: A retrospective study of the cytology was performed at the cytology section, Department of Anatomical Pathology. We received the samples of the cervical cancer screening form three departments, the outpatient Obstetrics – Gynecology, the tumor clinics and the family planning clinics between January 1, 2010 and December 20, 2012 using the Bethesda System 2001. Results: There were 20,293 case consisting of 6,678, 6,628 and 6,987 cases (in the year 2010, 2011 and 2012, respectively). The results were negative for intraepithelial lesion (NILM) of 97.4%. From this study, 522 cases (2.6%) were found abnormal, consisting of ASC-US/ASC-H/AGE 1.4%, LSIL 0.6%, HSIL/AIS 0.5% and the invasive malignancy 0.1%. The average age of women with ASC-US/ASC-H/AGC, LSIL, HSIL/AIS and malignancy were 45.9, 38.0,48.7 and 51.2 years, respectively. Conclusions: The results of abnormal Pap smear were found in 2.6%. The age intervals of highest prevalence of LSIL, HSIL/AIS and malignancy were 27-49, 36-62, 38-64 years old, respectively