The Prevalence of Chronic Kidney Disease in Periodic Health Check up at Maharat Nakhon Ratchasima Hospital
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Abstract
Background:Chronic kidney disease (CKD) is a major public health problem in Thailand. But no data about the prevalence of CKD has been reported in Nakhon Ratchasima Province. Objective: To determine the prevalence of CKD in Nakhon Ratchasima Province. Patients & Methods: The clinical and laboratory data from periodic checked up during 2006-2007 for the government officers were collected and descriptively analyzed. Results: The total of 6,814 government officers were completed the periodic checked up, with 63.4 percent were male. The median age was 46.0 (19 -87) years. According to the classification of stages of CKD by Kidney Disease Outcome Quality Initiative (K/DOQI), the prevalence of CKD is 14.3% by Modification of Diet in Renal Disease and 22.8% by Cockcroft Gault formula. Patients with diabetes mellitus, hypertension, hypercholesterolemia, hyperuricemia .overweight, and proteinuria were found in 17.2, 3.58 , 71.7, 43.5, 63.4, and 11%, respectively. Risk factors for CKD when use MDRD formula are age >60 years (odds ratio 3.3, 95% CI 2.07-5.25) , systolic and diastolic hypertension (odds ratio 3.37, 95% CI 2.60-4.34, and odds ratio 3.37, 95% CI 2.60-4.34), diabetes mellitus (odds ratio 4.88, 95% CI 2. 3.71-6.41) and when use Cockcroft-Gault formular risk factors are age >60 years (odds ratio 5.8, 95% CI 3.67-9.15) and diabtes mellitus (odds ratio 2.89, 95% CI 2. 2.21-3.78) Conclusion: CKD was not uncommon Nakhon Ratchasima Province. The Cockcroft-Gault and MDRD formula were different in detecting CKD in the present study. The proper formula to determine GFR may be considered. The exact prevalence should be study in future in other population. GFR value report from laboratory result may help for early detection of CKD.
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