Survival Analysis of Children with Primary Malignant Brain Tumor in Maharat Nakhon Ratchasima Hospital
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Abstract
Introduction: Brain tumor is the second common malignancy in children. Main treatment was surgery and radiotherapy. Objectives: To analyse survival rate and prognostic of brain tumor in children in Maharat Nakhon Ratchasima Hospital. Patients & Methods: The eligible medical records of patients with brain tumor treated between January 2001 and December 2005 were retrospectively reviewed. Results: Thirty brain tumor patients were analysed. The age range was 1.1-17.8 years (mean 10.13.9 years) The male : female ratio was 1 : 1 Brain tumors consisted of medulloblastoma 30%, brain stem tumor 20%, germ cell tumor 16.7%, astrocytoma 13.3%, ependymoma 6.7%, glioblastoma multiforme 6.7%, primitive neuroectodermal tumor 3.3%, and pituitary tumor (unspecified type) 3.3%. The overall 3-year survival rate was 47.6% (95% confidence interval 13.1-58.1). The overall 3-year survival rates of medulloblastoma, brain stem tumor and astrocytoma patients were 34.6%, 16.7% and 60% respectively. Conclusion: The overall 3-year survival rate of children with primary malignant brain tumor in Maharat Nakhon Ratchasima Hospital was similar to that of other studies except 3-year survival rate of medulloblastoma which was lower than that of other studies.
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