Crescentic Glomerulonephritis Associated with MPO-ANCA during Propylthiouracil Treatment : a Case report and Literatures Review
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Abstract
ANCA-related crescentic glomerulonephritis is an uncommon illness. It has become evident that ANCA, predominant of the P-ANCA type, can be detected in patients association with anti-thyroid (MPO-ANCA) during propylthiouracil (PTU) treatment. Although the serum creatinine level gradually decreased after cessation of PTU and immunosuppressive treatment, irreversible renal dysfunction persisted. Because of the widespread use of anti-thyroid medication, patients treated with PTU should be placed under vigilant observation by monitoring their urinalysis and serum creatinine level.
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