Antonomic Dysfunction in Hemodialysis Patients with Intradialysis Hypotension
Article Sidebar
Main Article Content
Abstract
Background: Autonomic dysfunction is considered a factor that contributes to dialysis-induced hypotension (DIH) Objective: To assess the autonomic dysfunction in DIH and non-dialysis induced hypotension (NDIH) patients by using the traditional autonomic function test. Material and Methods: Autonomic function tests were performed in both groups in Siriraj Hospital during September-November 2002. Result: Thirteen patients with DIH and 15 patients without DIH (NDIH) were studied. Sympathetic dysfunction was more common in both patient groups (DIH; 30.8% vs. NDIH; 46.7%), However there was no statistical difference between both groups, in either sympathetic or parasympathetic functions while parasympathetic dysfunction was less common (DIH; 7.7% vs. NDIH; 13.3%). Conclusion: The autonomic dysfunction by using the traditional autonomic function test was no difference between patients with or without dialysis induced hypotension.
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
References
Orofino L, Marcen R, Quereda C, Villafruela JJ, Sabater J, Matesanz R, et al. Epidemiology of symptomatic hypotension in hemodialysis: Is cool dialysate beneficial for all patients? Am I Nephrol 1990; 10: 177-80.
Daugirdas JT. Dialysis hypotension: a hemodynamic analysis. Kidney Int 1991; 39: 233-46.
Koomans HA, Blankestin PJ. Blood volume preservation in dialysis: tools and strategies. Nephrol Dial Transplant 1995; 10: 1791-3.
Kerch ES, Kronfield SJ, Unger A, Poooer RW, Cantor S, Cohn K. Autonomic insufficiency in uremia as a cause of hemodialysis-induced hypotension. N Eng! J Med 1974; 290:650-3.
Ewing DJ, Winney R. Autonomic function in patients with chronic renal failure on intermittent haemodialysis. Nephron 1975; 15: 424-9.
Ewing DJ, Campbell IW, Clarke BF. Assessment of cardiovascular effect in diabetic autonomic neuropathy and prognosis implication. Ann Intern Med 1980; 92: 308-11.
Baselli G, Cerutti S, Lombardi F, Malliani A, Merri M, Pagani M, et al. Heart rate variability signal processing: a quantitative approach as an aid to diagnosis in cardiovascular pathologies. Int J Biomed Comput 1987; 20: 51-70
Weise F, Heydenreich F, Runge U. Heart rate fluctuation in diabetic patients with cardiac vagal dysfion: a spectral analysis. Diabetic Med 1988; 5:324-7.
Converse RL Jr, Jacobson TN, Jost CMT, Victor RG. Paradoxical withdrawal of reflex vasoconstriction as a cause of hemodialysis-induced hypotension. J Clin Invest 1992;90:1657-65.
Perazella MA, Midodrine. A new therapy for intradialytic hypotension. Semin Dial 1997; 10: 245-7.
Low PA, Gilden JL, Freeman R, McElligott MA. For the Midodrine study group: Efficacy of midodrine vs placebo in neurogenic orthostatic hypotension: A randomized, double-blind multicenter study. JAMA 1997;277: 1046-51.