Risk Factors Associated with Osteoarthritis of the Knee: Studied Cases in Maharat Nakhon Ratchasima Hospital
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Abstract
Abstract: A hospital-based case-control study of the risk factors associated with osteoarthritis of the knee was conducted at Maharat Nakhon Ratchasima Hospital during August to September 1999. Cases were 210 patients with osteoarthritis of the knee and 210 controls who had other orthopedic conditions, aged 45 years or more who were registered at an orthopedic clinic. The information were collected by direct interviewing, using a structured questionnaire which included information regarding socio-demographic, BMI health history and health related behavior. The association between risk factors and osteoarthritis of the knee was analysed by the multiple logistic regression to control for the effects of age and gender. The results showed that a body mass index of 25.0 to 29.9 kg/m2 and > 30.0 kg/m2 increased the risk by 2.27 times (95% CI = 2.71 to 19.80 and 6.75 …… 95% CI = 2.71 to 16.80). Sitting postures such as kneeling, squatting, and Thai traditional sitting longer than 6 hours/week increased the risk by 20.90 times (95% CI = 2.77 to 40.80), 16.62 times (95% CI = 9.36 to 29.48) and 4.86 times (95% CI = 2.77 to 8.54), respectively. To reduce the risk of osteoarthritis of the knee, sitting postures such as kneeling, squatting, and Thai traditional sitting for ling duration should be avoided. Weight should be controlled to an optimal level.
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References
Sharma L, Hurwitz DE, Thonar EJ-MA, et al. Knee adduction moment, serum hyaluronan level, and disease severity in medial tibiofemofal osteoarthritis. Arthritis Rheum 1998; 41:1233-40.
Spector TD, Hart DJ. How serious is knee osteoarthritis? Ann Rheum Dis 1992;51:1105-6.
Chaiamnuay P, Darmawan J, Muirden KD, Assawatanabodee P. Epidemiology of rheumatic disease in rural Thailand: a WHO-ILAR COPCORD study. J Rheumatol 1998;25: 1382-7.
ฐิตเวทย์ ตุมราศวิน. โรคข้อเสื่อม. ใน: สุรวุฒิ ปรีชานนท์, สุรศักดิ์ นิลกาวงศ์, บรรณาธิการ. ตำราโรคข้อ. กรุงเทพฯ : เรือนแก้ว ; 2538. หน้า 360-74.
Felson DT, Chaisson CE. Understanding the relationship between body weight and osteoarthritis. Baillieres's Clinical Rheumatology 1997;11:671-9.
Cooper C, McAlindon T, Snow S, et al. Mechanical and constitutional risk factors for symtomatic knee osteoarthritis. J Rheumatol 1994;21:307-13.
สุจิตรา ไชยพัฒนะพฤกษ์. ปัจจัยที่มีความสัมพันธ์กับ การเกิดโรคข้อเข่าเสื่อม [วิทยานิพนธ์ปริญญาวิทยาศาสตรมหาบัณฑิต สาขาวิชาชีวสถิติ]. กรุงเทพฯ: บัณฑิตวิทยาลัย, มหาวิทยาลัยมหิดล; 2532.
ชูเกียรติ วิวัฒน์วงศ์เกษม. การกำหนดขนาดตัวอย่างสำหรับงานวิจัย. วารสารวิจัยวิทยาศาสตร์การแพทย์ 2537;8:121-46.
Brandt KD. Osteoarthritis. In: Fauci AS, Braunwald E, Isselbacher KJ,et al,editors. Principles of internal medicine. 14th ed. New York: McGraw-Hill;1998. p.1935-41.
Hart DJ, Doyle DV, Spector TD. Incidence and risk factors for radiographic knce osteoarthritisin middle-aged women. Arthritis Rheum 1999; 42:17-24.
Martin K, Lethbridge-cejku M, Muller DC, et al. Metabolic correlates of obesity and radiographic features of knee osteoarthritis: data from the Baltimore longitudinal study of aging. J Rheumatol 1997;24:702-7.
Felson DT, Zhang Y, Hannan M, et al. Risk factors for incident radiographic knee osteoarthri tis in the elderly. Arthritis Rheum 1997;40:728-33.
Davis MA, Ettinger WH, Neuhaus IM, Mallon KP. Knee osteoarthritis and physical functioning: evidence from NHANES I epidemiologic follow up study. J Rheumatol 1991;18:591-8.
Zhang Y, McAlindon TE, Hannan MT, et al. Estrogen replacement therapy and worsening of radiographic knee osteoarthritis. Arthritis Rheum 1998;41:1867-73.
Manninen P, Riihimaki H, Heliovaara M, Makela P. Overweight, gender and knee osteoarthritis [abstract]. Int J Obes Relat Metab Disord 1996;20:595-7.
Schouten JS, Ouweland FA, Valkenburg HA. A 12-year follow up study in the general population on prognostic factors of cartilage loss in osteoarthritis of the knee. Ann Rheum Dis1992;9:932-7.
Vingard E, Alfredson L, Goldie I, Hogstedt C. Occupation and osteoarthritis of the hip and knee. Int J Epidemiol 1990; 20:1025-31.
Mactzel A, Makela M, Hawker G, Bombardier C. Osteoarthritis of the hip and knee and mechanical occupation exposure: a systematic overview of the evidence. J Rheumatol 1997;24:1599-607.
Cicuttini FM, Baker JR, Spector TD. The association of obesity with osteoarthritis of the hand and knee in women: a twin study. J Rheumatol 1996;23:1221-6.
Sandmark H, Hogstedt C, Lewold S, Vingard E. Osteoarthrosis of the knee in men and women in association with overweight, smoking, and hormone therapy. Ann Rheum Dis 1998:151-5.
Spector TD, Hart DJ, Doyle D. Incidence and progression of osteoarthritis in women with unilateral knee disease in the general population: the effect of obesity. Ann Rheum Dis 1994;53: 565-8.
Davis MA, Ettinger WH, Neuhaus IM. The rolc of metabolic factors and blood pressure in the association of obesity with osteoarthritis of the knee. J Rheumatol 1988;15:1827-32.
Cooper C, McAlindon T, Snow S, et al. Mechanical and constitutional risk factors for symtomatic knee osteoarthritis. J Rheumatol 1994;21:307-13.
Hochberg MC, Lethbridge CM, Scott WW Jr, Reichle R, Plato CC, Tobin JD. The association of body weight, body fatness and body fat distribution with ostecarthritis of the knee: data from the Baltimore longitudinal study of aging. J Rheumatol 1995;22:488-93.
Hart DJ, Doyle DV, Spector TD. Association between metabolic factors and knce ostcoarthritis in women?: The Chingford study. J Rheumatol 1995;22:1118-23.