Prevalence of H.pylori in Peptic Ulcer Patients, Maharat Nakhon Ratchasima Hospital

Abstract

Endoscopic biospy of antrum and corpus were obtained from 304 peptic ulcer patients to determine the prevalence of H. pylori infection at the Maharat Nakhon Ratchasima Hospital. The CLO (Campylobacter-like organisms) test, culture, and histology were used as diagnostic tests. The study revealed that the prevalence of H. pylori infection in peptic ulcer patients was 69.1%. H. pylori infection was related to diagnosis. DU had the highest prevalence of H. pvlori infection (90.4%), GU and NUD were less frequently associated with H. pylori infection (68.5% and 56.8% respectively). There was association between sex and H. pylori infection, males were infected more than females (Odds ratio-3.54, 95% Cl-2.00-6.27). But there were not association between H. pylori infection and other socioeconomic factors, i.e., age, residence, education, and income of patients. The sensitivity of CLO test, culture, and histology were 57.6%, 85.2%, and 78.5% respectively and the specificity of three procedures were 89.4%, 100%, and 100% respectively. The positive predictive value of CLO test, culture, and histology were 92.4%, 100%, 100%, respectively. The negative predictive value of CLO test, culture, and histology were 48.6%, 75.2%, 67.6% respectively.