Yellow fever vaccine administration in egg anaphylaxis child

Abstract

Background: Administration of yellow fever vaccine in patients with egg allergy is contraindicated. However, there are exceptional circumstances needed to administer yellow fever in patients with egg allergy. Herein, we reported the success of graded doses yellow fever vaccine administration in egg anaphylaxis child.
Methods: A case report                                                                                                                                                                                                Results: Sixteen months Thai-Nigeria boy diagnosed with egg anaphylaxis at 10 months old was consulted for yellow fever vaccine administration for traveling to Nigeria. He was evaluated for the possibility to have a hypersensitivity reaction to the vaccine using skin prick test and intradermal skin test, and the result showed positive skin test. As a result, he hasreceived the yellow fever vaccine by 5 steps graded dose. He was given chlorpheniramine and hydrocortisone 30 minutes before giving the first dose. The child tolerated well for the vaccine administration with no adverse reaction.
Conclusions: Yellow fever vaccination in egg anaphylaxis children using graded doses protocol is feasible. This should be an alternative method for egg allergy patient who needs to be vaccinated yellow fever in the future.