Pediatric anaphylaxis in Queen Sirikit National Institute of Child Health
Keywords:
Pediatric anaphylaxis, allergen, clinical manifestation, managementAbstract
Background: Anaphylaxis is an immediately life-threatening systemic hypersensitivity reaction. The incidence of anaphylaxis trends to be increasing especially in children. There are few studies of pediatrics anaphylaxis, particularly in Thailand.
Objective: To investigate the triggers, clinical manifestation, treatment and outcome of anaphylaxis in Queen Sirikit National Institute of Child Health.
Method: A retrospective descriptive study through retrospective chart review, based on ICD-10 between January 2007 and May 2021.
Results: The 200 anaphylactic patients were analyzed. The mean age is 6.96±4.3 years old. (The youngest is 4 days and the oldest is 15 years and 5 mounts). 48.5% of patients had a personal history of allergic diseases, most common was allergic rhinitis. The most common triggers were foods (56%), followed by idiopathic or unknown allergen (16.5%), insects bite (14%), mite immunotherapy (9%) and drugs(7%). Mucocutaneoussymptom, including urticaria and angioedema were mainly reported symptoms(96.5%), followed by respiratory symptoms(76.4%).Among the respiratory symptoms, breathing difficulty and bronchospasm were most common in all age group except in young children aged 0-2 years old who mainly presented with coryzalsymptoms.Adrenaline injections were prescribed in most of patients (93.4%). The biphasic anaphylaxis occurred in 7 patients (4.6%).
Conclusions: Anaphylaxis commonly occurred in school age. Foods were the common triggers especially seafood. The triggers and clinical manifestations in young children may differ from other age groups
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