Nutritional Status in Patients with Systemic Sclerosis at Scleroderma Clinic, Srinagarind University Hospital, Thailand
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Abstract
Objectives: Systemic sclerosis (SSc) is a connective tissue disease that involves multiple organs. Recently, there has been a lack of Thailand data on the prevalence, severity, nutritional status and risk factors of malnutrition in SSc. Therefore, we designed this research to study prevalence, severity, nutritional status and malnutrition risk factors in SSc at Srinakarin University Hospital, Thailand.
Method: This study was a non-randomized cross-sectional study conducted in the scleroderma clinic at Srinakarin University Hospital between 2011-2012. After obtaining informed consent, the patient was followed up in the next two months for a venous blood sample and evaluation of nutritional status by asking for a history and performing a physical exam.
Results: Regarding nutritional status, SSc patients who were malnourished were 34 (46.58%). In the malnutrition group, we found that severe malnutrition was 13 (17.81%). However, multivariate analysis was insignificant regarding risk factors in the malnutrition group; the severe malnutrition group showed that difficulty chewing and dental carries were statistically significant.
Conclusions: In the scleroderma clinic at Srinakarin University Hospital, SSc patients have malnutrition, and some have severe malnutrition. We suggest that difficult chewing and dental carries were risk factors in the severe malnutrition group. Perhaps good oral hygiene may protect against severe malnutrition in SSc patients.
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(ใส่ข้อความเดียวกันกับ ก๊อปปี้ไลน์ก็ได้)ดูตัวอย่างได้ที่หน้าบทความ---บทความนี้ตีพิมพ์เป็นลิขสิทธื์ของใคร...
References
Klippel JH. Primer on the rheumatic diseases. New York, NY: Springer; 2008. Available from: http://dx.doi.org/10.1007/978-0-387-68566-3.
Firestein GS, Kelley WN. Kelley's textbook of rheumatology. 8th ed. Philadelphia, PA: Saunders/Elsevier; 2009. 2 v. (xxiv, 1902, li p.) p.
Foocharoen C, Nanagara R, Kiatchoosakun S, Suwannaroj S, Mahakkanukrauh A. Prognostic factors of mortality and 2-year survival analysis of systemic sclerosis with pulmonary arterial hypertension in Thailand. Int J Rheum Dis. 2011;14(3):282-9.
Ioannidis JP, Vlachoyiannopoulos PG, Haidich AB, Medsger TA, Jr., Lucas M, Michet CJ, et al. Mortality in systemic sclerosis: an international meta-analysis of individual patient data. Am J Med. 2005;118(1):2-10.
Steen VD, Medsger TA. Changes in causes of death in systemic sclerosis, 1972-2002. Ann Rheum Dis. 2007;66(7):940-4.
Panicheewa S, Chitrabamrung S, Verasertniyom O, Vanichaphantu M, Kraisit SO, Chiewsilp P, et al. Diffuse systemic sclerosis and related diseases in Thailand. Clin Rheumatol. 1991;10(2):124-9.
Szamosi S, Szekanecz Z, Szucs G. Gastrointestinal manifestations in Hungarian scleroderma patients. Rheumatol Int. 2006;26(12):1120-4.
Bharadwaj S, Tandon P, Gohel T, Corrigan ML, Coughlin KL, Shatnawei A, et al. Gastrointestinal Manifestations, Malnutrition, and Role of Enteral and Parenteral Nutrition in Patients With Scleroderma. J Clin Gastroenterol. 2015;49(7):559-64.
Forbes A, Marie I. Gastrointestinal complications: the most frequent internal complications of systemic sclerosis. Rheumatology (Oxford). 2009;48 Suppl 3:iii36-9.
Sallam H, McNearney TA, Chen JD. Systematic review: pathophysiology and management of gastrointestinal dysmotility in systemic sclerosis (scleroderma). Aliment Pharmacol Ther. 2006;23(6):691-712.
Marie I, Ducrotte P, Denis P, Hellot MF, Levesque H. Outcome of small-bowel motor impairment in systemic sclerosis--a prospective manometric 5-yr follow-up. Rheumatology (Oxford). 2007;46(1):150-3.
Baron M, Hudson M, Steele R, Canadian Scleroderma Research G. Malnutrition is common in systemic sclerosis: results from the Canadian scleroderma research group database. J Rheumatol. 2009;36(12):2737-43.
Krause L, Becker MO, Brueckner CS, Bellinghausen CJ, Becker C, Schneider U, et al. Nutritional status as marker for disease activity and severity predicting mortality in patients with systemic sclerosis. Ann Rheum Dis. 2010;69(11):1951-7.
Baker JP, Detsky AS, Wesson DE, Wolman SL, Stewart S, Whitewell J, et al. Nutritional assessment: a comparison of clinical judgement and objective measurements. N Engl J Med. 1982;306(16):969-72.
Detsky AS, McLaughlin JR, Baker JP, Johnston N, Whittaker S, Mendelson RA, et al. What is subjective global assessment of nutritional status? JPEN J Parenter Enteral Nutr. 1987;11(1):8-13.
Jeejeebhoy KN, Detsky AS, Baker JP. Assessment of nutritional status. JPEN J Parenter Enteral Nutr. 1990;14(5 Suppl):193S-6S.