Metastatic Squamous Cell Carcinoma of the Cervix Presenting as Polycystic Lesions of the Liver: A case Report

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Sarun Sompornserm
Somchai Insiripong
Siraya Kitiyodom

Abstract

          The cervical cancer is common among Thai females and in its advanced stage,it is more commonly found as the local infiltration into the surrounding organs than as the distant multiple metastases via the blood stream. The isolated liver metastasis from the cervical cancer has been rarely reported especially the multiple cystic lesions due to the squamous cell carcinoma as in our patient. She was 56-year-old Thai woman who presented with mild right upper quadrant pain and low graded fever for a month. The computerized tomography of the abdomen showed multiple cysts with solid part and peripheral enhancement at the segments 6, 7, 8 of the liver, the largest one was 5x6 cm in size. Eight months ago, she was pathologically proved to have the squamous cell carcinoma of the cervix, moderate differentiation, stage IIIB. And she was medically treated with cis-platin followed by BCT until complete remission was achieved in 4 months. But her liver biopsy specimen yielded by the ultrasonography guidance was pathologically proved to bethe squamous cell carcinoma, the presumably primary site was the cervix. She was again treated with cis-platin with higher dosage. In general, the liver metastasis is always solid, the multiple cystic lesions in the liver in the combination with fever may remind the clinicians of the bacterial liver abscess or metastatic adenocarcinoma from the colon or ovary. Only the pathology of the tissue biopsy is able to clearly differentiate the definite diagnosis of theseentities.

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How to Cite
Sompornserm, S., Insiripong, S. . ., & Kitiyodom, S. . (2024). Metastatic Squamous Cell Carcinoma of the Cervix Presenting as Polycystic Lesions of the Liver: A case Report. Maharat Nakhon Ratchasima Hospital Journal, 38(2), 109–112. Retrieved from https://he04.tci-thaijo.org/index.php/MNRHJ/article/view/1587
Section
Case Report

References

Sarikapan W. Epidemiologic report of gynecologic cancer in Thailand. J Gynecol Oncol 2009; 20: 81-3.

Lax S. Histopathology of cervical precursor lesions and cancer. Acta Dermatovenerol Alp Pannonica Adriat 2011; 20: 125-33.

Chao A, Lin CT, Lai CH. Updates in systemic treatment for metastatic cervical cancer. Curr Treat Options Oncol 2014; 15: 1-13.

Elit L, Fyles AW, Oliver TK, Devries-Aboud MC, Fung-Kee-Fung M. Follow-up for women after treatment for cervical cancer. Curr Oncol 2010; 17: 65-9.

Mortele KJ, Ross PR. Cystic focal lesions in the adult: Differential CT and MR imaging features. Radio Graphics 2010; 21: 895-910.

Galgano MT, Castle PE, Atkins KA, Brix WK, Nassau SR, Stoler MH. Using biomarkers as objective standards in the diagnosis of cervical biopsies. Am J Surg Pathol 2010; 34: 1077-87.

Ramia JM, De la Plaza R, Quinones J, Veguillas P, Adel F, Garcia-Parreno J. Liver metastases from gynecological cancers: time to resection? Surg Sci 2012; 3: 120-5.

Kim GE, Lee SW, Suh CO, Park TK, Kim JW, Park JT, et al. Hepatic metastases from carcinoma of the uterine cervix. Gynecol Oncol 1998;70:56-60.

Zhao R, Zhu K, Wang R, Gao J, Cui K, Yu F, et al. Primary squamous cell carcinoma of the liver: A case report and review of the literature. Oncol Lett 2012; 4: 1163-6.

Yuki N, Hijikata Y, Kato M, Kawahara K, Wakasa K. Squamous cell carcinoma as a rare entity of primary liver tumor with grave prognosis. Hepatol Res 2006; 36: 322-7.