Factors Associated with Success of Treatment among New Smear-Positive Pulmonary Tuberculosis Patients in Pakchong Nana Hospitals

Abstract

Objectives: To find out the factors associated with success of treatment among new smear-positive pulmonary tuberculosis in Pakchong Nana Hospital, Pak Chong, Nakhon Ratchasima Province. Patients & Method: This cross-sectional retrospective descriptive study collected the data of patients from 3 sources; 1) TBCM program including demographic characteristics, screening, treatment and home visit, 2) TB Clinic’s documents showing the motivation and descriptive data, and 3) Information electronic systems from Pakchong Nana Hospital & Sub-district health promoting hospitals in Pak Chong Amphoe showing the data of service network within the area between 1st October 2009 and 30th September 2013. Results: There were 557 participants and 416 were males (74.7%) with age range of 25-50 years old, no comorbidity 452 patients (81.1%), HIV infection 62 patients (11.1%), CD4 less than 100 cell/mm³ 26 patients (42.0%) and on ARV 29 patients (46.8%). TB patients with HIV infection had a significantly lower success rate than those without HIV infection (adjusted OR 0.3, 95% confidence interval 0.1, 0.5). TB patients receiving programmed TB treatment had significantly higher success rate than those without treatment (adjusted OR 21.8, 95% confidence interval 8.5, 55.4). TB patients admitting home visit had significantly higher success rate than those without admittance (adjusted OR 10.8, 95% confidence interval 4.2, 27.7). And TB patients accepting the screening had significantly higher success rate than those without acceptance (adjusted OR 3.4, 95% confidence interval 1.5, 7.7). Conclusions: Free from HIV infection, anti-TB acceptance, screening and home visit admittance are significantly associated with success of treatment among new smear-positive pulmonary tuberculosis patients.