Histopathologic diagnosis of lymph node biopsies in Maharat Nakhon Ratchasima Hospital
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Abstract
Background: Lymphadenopathy is very common in clinical practice. And it needs pathological examination formaking definite diagnosis. Aims: To study the prevalence of pathological diagnoses of lymph nodes according tosites and age group particularly from the patients with HIV infection or history of cancers. Patients & Method:This retrospective study collected data from medical records, pathological reports, and the review of lymph nodespecimens between January 1, and December 31, 2011. Results: There were 455 specimens of lymph node. Themost common site was the cervical, followed by supraclavicular and inguinal regions. The most common pathologicaldiagnosis was metastatic carcinoma, followed by granulomatous lymphadenitis and malignant lymphoma/leukemia. Among malignant lymphoma/leukemia, diffuse large B-cell lymphoma was the most frequent subtype,followed by Hodgkin’s lymphoma and follicular lymphoma. For cervical lymph nodes, granulomatous lymphadenitiswas the most common pathology while metastatic carcinoma was the commonest diagnoses of supraclavicularand inguinal lymph nodes. Granulomatous lymphadenitis was also the most common cause of lymphadenopathyin HIV patients and in patients between 0-40 years of age. In patients with history of cancer and patientsover 40 years of age, metastatic carcinoma was the majority cause of lymphadenopathy. Conclusion: Metastaticcarcinoma was the most common cause of lymphadenopathy in this study. This chance was high in supraclavicularlymph nodes, elderly patients and patients with history of cancer. Granulomatous lymphadenitis was thecommon cause of lymphadenopathy in the young and HIV patients.
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