The Prevalence and the Associated Factors of Sleep-Related Problems in Patients with Parkinson’s Disease at Maharat Nakhon Ratchasima Hospital
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Abstract
Objective: To evaluate the prevalence and identify the associated factors of sleep-related problem in patient with Parkinson’s disease at Maharat Nakhon Ratchasima Hospital. Patients & Method: A cross sectional study in Parkin-son’s disease patients at Maharat Nakhon Ratchasima Hospital were done during January-December 2010. Sleep problems were assessed by using the modified Parkinson’s disease sleep scales (MPDSS) questionnaires. The baseline characters and the expected associated factors were collected. All values were analyzed for identify the associated factors with sleep-related problems. Results: Eighty-five subjects were enrolled in the study. The prevalence of sleep-related problems was 54.1%. The most frequent sleep problem was nocturia and the second most common problem was sleep maintenance. The patients had received levodopa more than 500 mg/d were associated with sleep-related problems (adjusted odds ratio =3.2, 95%CI 1.23-8.29). Conclusion: The prevalence of sleep-related problems in patient with Parkinson’s disease at Maharat Nakhon Ratchasima Hospital was 54.1%. Nocturia is the most frequent sleep problem. The sleep-related problems were associated with high dosage of levodopa per day.
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