The Experience of Acute Stroke Therapy with rtPA in Maharat Nakhon Ratchasima Hospital
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Abstract
Objective: To describe the experience in thrombolytic recombinant tissue plasminogen activator (rtPA) therapy in acute ischemic stroke at Maharat Nakhon Ratchasima Hospital. Patients and Methods: The patients with acute ischemic stroke who presented within 3 hours of onset were screened under Stroke Fast Tract Program. Those who were eligible were treated with intravenouse recombinant tissue plasminogen activator (rtPA). Both neurological and general examination with the National Institute Health Stroke Scale, modified Rakin Scale, and Barthel index as well as computerized tomography of the brain were recorded, prior to give rtPA and 24 hours after treatment. Result: There were five patients with acute stroke receiving intravenous rtPA. All had stroke in the middle cerebral artery territory with cardiac AF. Three of five patients had complete recovery, the other two had improvement but complicated with bleeding in the brain. Conclusion: Intravenous thrombolysis can be given at Maharat Nakhon Ratchasima Hospital with good outcome. Therefore, the program should be extended.
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