HIV in Pregnancy in Maharat Nakhon Ratchasima Hospital

Abstract

Background: Maharat Nakhon Ratchasima Hospital (MNRH) has implemented the program of Ministry of Public Health for prevention of mothers-to-child HIV transmission (PMTCT). The activities consisted of giving antiretroviral drugs (ARV) to HIV positive mothers during pregnancy and/or during labour, early antiretroviral treatment and formula feeding in infants born to HIV positive mothers. Objectives: To find the prevalence of HIV infection in pregnancy and to evaluate the result of operation according to PMTCT in MNRH. Patients and Methods: The records of all pregnant women between 1 January 2002 to 31 December 2005 were retrospectively analyzed. Results: The prevalances of HIV in pregnancy gradually decreased every year. In 2005, it was 0.92% and tended to be prominent in young age group. For implementation of PMTCT, there were 293 HIV positive pregnant women, 92.8% of them had attended antenatal care (ANC) whereas 67.6% receiving ARV during labour. There were 295 infants born to HIV positive mothers, 74.9% by vaginal delivery, 93.2% receiving ARV, 52.5% receiving formula feeding. Only 75 infants (25.4%) were investigated for HIV status and 4% were positive. Only 106 mothers and their infants had fully complied PMTCT program and their HIV transmission rate was decreased to 2.1%. Conclusion: The Prevalence of HIV infection in pregnancy was 0.92% in year 2005. And the implementation of PMTCT resulted in decrease of HIV transmission from mother to infant in MNRH.