Factors Affecting an Acute Exacerbation among COPD patients in Phaholpolpayuhasena Hospital, Kanchanaburi
Keywords:
acute exacerbation, hospitalization, chronic obstructive pulmonary diseaseAbstract
Objectives: To study the prevalence of acute COPD exacerbations and factors associated with acute exacerbation in Phaholpolpayuhasena Hospital.
Methods: An analytical cross-sectional study was conducted on patients with COPD who received treatment at the COPD clinic, Phaholpolpayuhasena Hospital, Kanchanaburi Province, from January to April 2024. A total of 200 patients were included. Data on potential factors influencing acute exacerbations were collected. Data were analyzed using chi-square or Fisher's exact tests and multivariate analysis with multiple logistic regression.
Conclusions: The prevalence of acute COPD exacerbation in Phaholpolpayuhasena Hospital within 1 year is 16.5%. Factors associated with acute COPD exacerbations were pollution around the house and home oxygen therapy.
References
Halpin DMG, Celli BR, Criner GJ, Frith P, López Varela MV, Salvi S, et al. The GOLD Summit on chronic obstructive pulmonary disease in low- and middle-income countries. Int J Tuberc Lung Dis. 2019;23(11):1131-41.
Saeid S, Kristin C-C, Maryam N, Seyed Aria N, Mark JMS, Javad Ahmadian H, et al. Burden of chronic obstructive pulmonary disease and its attributable risk factors in 204 countries and territories, 1990-2019: results from the Global Burden of Disease Study 2019. BMJ. 2022;378:e069679.
Mathers CD, Loncar D. Projections of global mortality and burden of disease from 2002 to 2030. PLoS medicine. 2006;3(11):e442.
Kessler R, Partridge MR, Miravitlles M, Cazzola M, Vogelmeier C, Leynaud D, et al. Symptom variability in patients with severe COPD: a pan-European cross-sectional study. Eur Respir J. 2011;37(2):264-72.
Elliott MW, Adams L, Cockcroft A, MacRae KD, Murphy K, Guz A. The language of breathlessness. Use of verbal descriptors by patients with cardiopulmonary disease. Am Rev Respir Dis. 1991;144(4):826-32.
Laviolette L, Laveneziana P. Dyspnoea: a multidimensional and multidisciplinary approach. Eur Respir J. 2014;43(6):1750-62.
Cho SH, Lin HC, Ghoshal AG, Bin Abdul Muttalif AR, Thanaviratananich S, Bagga S, et al. respiratory disease in the Asia-Pacific region: Cough as a key symptom. Allergy Asthma Proc. 2016;37(2):131-40.
Goërtz YMJ, Looijmans M, Prins JB, Janssen DJA, Thong MSY, Peters JB, et al. Fatigue in patients with chronic obstructive pulmonary disease: protocol of the Dutch multicentre, longitudinal, observational FAntasTIGUE study. BMJ Open. 2018;8(4):e021745.
Dransfield MT, Kunisaki KM, Strand MJ, Anzueto A, Bhatt SP, Bowler RP, et al. Acute Exacerbations and Lung Function Loss in Smokers with and without Chronic Obstructive Pulmonary Disease. Am J Respir Crit Care Med. 2017;195(3):324-30.
Hoogendoorn M, Feenstra TL, Hoogenveen RT, Al M, Mölken MR. Association between lung function and exacerbation frequency in patients with COPD. Int J Chron Obstruct Pulmon Dis. 2010;5:435-44.
Wedzicha JA, Seemungal TA. COPD exacerbations: defining their cause and prevention. Lancet. 2007;370(9589):786-96.
Hewitt R, Farne H, Ritchie A, Luke E, Johnston SL, Mallia P. The role of viral infections in exacerbations of chronic obstructive pulmonary disease and asthma. Ther Adv Respir Dis. 2016;10(2):158-74.
Fan X, Dong T, Yan K, Ci X, Peng L. PM 2.5 increases susceptibility to acute exacerbation of COPD via NOX4/Nrf2 redox imbalance-mediated mitophagy. Redox Biol. 2023;59:102587.
MacLeod M, Papi A, Contoli M, Beghé B, Celli BR, Wedzicha JA, et al. Chronic obstructive pulmonary disease exacerbation fundamentals: Diagnosis, treatment, prevention and disease impact. Respirology. 2021;26(6):532-51.
Hogea SP, Tudorache E, Fildan AP, Fira-Mladinescu O, Marc M, Oancea C. Risk factors of chronic obstructive pulmonary disease exacerbations. Clin Respir J. 2020;14(3):183-97.
ชมขวัญ แก้วพลงาม, ณัฐวดี อินทเเสน, ภานุพงษ์ อุ่นเรือนงาม, ปาริชาติ นิยมทอง. ปัจจัยพยากรณ์ที่มีความสัมพันธ์ต่อการเกิดภาวะกำเริบเฉียบพลันในผู้ป่วยโรคปอดอุดกั้นเรื้อรัง. วารสารโรงพยาบาลแพร่. 2565;30(1):99-111.
Downloads
Published
How to Cite
Issue
Section
License
Copyright (c) 2025 Phaholpolpayuhasena Hospital
This work is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License.
บทความที่ได้รับการตีพิมพ์เป็นลิขสิทธิ์ของโรงพยาบาลพหลพลพยุหเสนา
ข้อความที่ปรากฏในบทความแต่ละเรื่องในวารสารวิชาการเล่มนี้เป็นความคิดเห็นส่วนตัวของผู้เขียนแต่ละท่านไม่เกี่ยวข้องกับโรงพยาบาลพหลพลพยุหเสนาและบุคลากรท่านอื่น ๆ ในโรงพยาบาลฯ แต่อย่างใด ความรับผิดชอบองค์ประกอบทั้งหมดของบทความแต่ละเรื่องเป็นของผู้เขียนแต่ละท่าน หากมีความผิดพลาดใด ๆ ผู้เขียนแต่ละท่านจะรับผิดชอบบทความของตนเอง
Phaholpolpayuhasena Hospital