อาการแสดงเชื้อก่อโรคและความไวต่อยาต้านจุลชีพ ในผู้ป่วยเด็กโรคติดเชื้อทางเดินปัสสาวะ ของโรงพยาบาลพหลพลพยุหเสนา

Sirirat  Assawalerknun

Authors

Sirirat Assawalerknun Pediatric department, Phaholpolpayuhasena Hospital

Abstract

Urinary tract infection is a common infection in children. Delayed diagnosis and inappropriate treatment may lead to renal scarring, hypertension and chronic kidney disease. Escherichia coli is the most common pathogen. Antimicrobial resistance of urinary pathogens is increasing worldwide. Knowledge of local etiologic agents and antibiotic susceptibility patterns is important for choosing appropriate treatment.

Objectives To study antibiotic susceptibility patterns, common bacterial pathogens and congenital anomalies of kidneys and the urinary tract. Methods This is a retrospective review of medical records of children with urinary tract infection, aged 1 month to 14 years old from January 2015 to December 2021 in Phaholpolpayuhasena hospital.

Results Ninety four patients were included. Fourty four patients (46.81%) were male. The median age was 1.04 (0.17, 14.33) years. The most common pathogen was Escherichia coli (89.36%), of which 26.6% were ESBL producing organisms. Results of antimicrobial susceptibility analysis for Escherichia coli to antibiotics are as follows: ampicillin 10.53%, ceftriaxone 72.62% and amikacin 100%. Ultrasound was performed in 85 cases and 20 patients (23.53%) presented hydronephrosis. VCUG was performed in 33 cases and 7 patients (21.21%) presented VUR. The ESBL producing group showed significantly higher rates of antibiotic treatment and hospitalization within the previous3 months, a longer duration of parenteral antibiotics and change of antibiotics during treatment.

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