Clinical manifestation of patients who infected with Plasmodium Vivaxmalaria

Abstract

Malaria is a protozoan infection transmitted to humans by Anopheles mosquito. P. Vivax is most common malaria in Thailand. This study is to demonstrate clinical characteristics and treatment results of P. Vivax in Kanchanaburi province.

Results, there is equal number of male and female patients. Most of them did not have underlying diseases. They relatively came in with low blood pressure. Most common symptoms were fever (97.70%), shortness of breath (33.30%), and headache (25.60%). In addition, other symptoms may occur slightly, such as muscle pain and jaundice. Consistent with the results of laboratory tests, which found to have a slight increase in Total Bilirubin (1.90 ± 1.60 u/mL), a slight increase in Direct Bilirubin (0.80 ± 0.90 u/mL) and a mean increase in blood sugar of 178.3 ± 12.56 mg/mL. Red blood cells were found in the urine. But complete blood count (CBC) and liver function (LFT) were all within normal limits.

According to a study of P.vivax-infected patients in Kanchanaburi province, 51.16% had  complications, (66 out of 129 cases). 52 (40.30%) had low blood pressure. 18 (14%) had anemia.For severe complications, 11 (8.5%) had respiratory failure. 12 (9.30%) had metabolic acidosis, and 1 death (0.8%) from muti-organ failure. All patients received the standard treatment of chloroquine together with primaquine. The treatment results in this study had 99.20% cure

In conclusion, Kanchanaburi has good standard treatment and care according to WHO guidelines. Even though, recommendation to prevention P. Vivax infection is the prevention measures against mosquito bite such as avoid travel in mosquito area, repellent and insecticide.